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B12 deficiency can also lead to the destruction of immature red blood cells in the bone marrow, which can cause jaundice (yellowing of the skin and whites of the eyes)

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Guideline 2: Maintenance Dosing Schedules After the first phase, patients move to a maintenance dosing schedule for vitamin B12 therapy

Metformin Use and Vitamin B12 Deficiency: Untangling the Association

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