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PTC is the most common form and is characterized by relatively simple genetic mutations, which primarily activate signaling through the MAPK pathway [36], such as BRAFV600E (60%), RAS (15%), and gene fusions involving BRAF, RET, NTRK, and ALK (12%) [37]
Damanti S, Bourron O, Doulazmi M, et al
Trujillo, M., Alvarez, M
Pharmacological characterization of opioid effects in the rat hippocampal slice
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