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Being rich in membranes of the synaptic terminals, DHA has been considered to be important for the function of neurochemical transmission

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We report that GPX4 is co-localized with neuromelanin in SN dopamine neurons, decreased in PD midbrain, and associated with dystrophic axons in PD putamen

Conversely, zinc deficiency or chelation of tissue zinc improves anti-tumor immunity and enhances responses to immunotherapies such as PD-1, particularly in melanoma models [328]