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Human 1 type IV collagen NC1 domain exhibits distinct antiangiogenic activity mediated by 11 integrin

Among these new therapeutic options, tirzepatide has gathered significant interest in the scientific and medical community as the first member of a new class of drugs characterized by their ability to selectively bind and activate the receptors for the intestinal hormones GIP and GLP-1

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Tirzepatide activates both GIP and GLP-1 receptors , triggering changes in gastric emptying, insulin secretion, and appetite regulation

Lin L, Saha PK, Ma X, et al