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Excessive mitochondrial fission in tumor cells triggers oxidative stress, leading to a sharp increase in reactive oxygen species (ROS), which in turn promotes lipid peroxidation and facilitates ferroptosis [55]

191,192 Following the activation of GLP-1R, the subunits of GPCRs can directly activate Class I PI3Ks

Academic Press, pp 141166 Purich K, Dang JT, Poonja A et al (2020) Intraoperative fluorescence imaging with indocyanine green in hepatic resection for malignancy: a systematic review and meta-analysis of diagnostic test accuracy studies

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Additionally, they modulate the MAPK and JAK/STAT pathways through suppression of ERK and JNK phosphorylation, as well as STAT1 activation, thereby reducing the release of pro-inflammatory cytokines such as TNF- and IL-1 (Shi et al., 2017

10.1007/s10565-008-9115-5 34 FarooqM
