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[1] So far, 26 different inherited mutations in the extracellular matrix gene 1 have been reported in lipoid proteinosis

The regions proposed to govern substrate accessibility of the NTD from hNPC1 differ from what is proposed here for the NTD (Fig S7A), particularly helix 3, helix 7, and helix 8 of the NTD from hNPC1, all at the top of sterol opening, which excludes the ridge-forming mobile loop of the NTD (33)

10.3238/arztebl.2019.0825 194 ParkM

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Addition of daratumumab to lenalidomide, bortezomib, and dexamethasone for transplantation-eligible patients with newly diagnosed multiple myeloma (GRIFFIN): final analysis of an open-label, randomised, phase 2 trial