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6101, et seq

Fibroids occur when estrogen becomes dominant, with progesterone levels lowered

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This oxidant stress causes activation of a MAP kinase cascade in the cytosol ultimately leading to phosphorylation of c-jun N-terminal kinase (P-JNK), translocation of P-JNK to the mitochondria [34], and binding to the anchor protein Sab [35] for amplification of the mitochondrial oxidant stress and peroxynitrite formation in the mitochondrial matrix [33, 36]

[DOI] [PubMed] [Google Scholar] 26.van der Vliet A., ONeill C.A., Cross C.E., Koostra J.M., Volz W.G., Halliwell B., Louie S