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M.MazzantiM.et al

Rintatolimod: toll-like receptor 3 (TLR3) agonist for ME/CFS therapy By activating TLR3, rintatolimod triggers a type I interferon-mediated antiviral response, which upregulates effector proteins such as 2-5 oligoadenylate synthetase and protein kinase R to degrade viral ribonucleic acid (RNA) and inhibit translation, collectively enhancing the hosts antiviral defense

The expansion of Hasmonean Judea took place gradually

221 (2), e201911005

Biomaterials 35, 143151

No obvious toxicity has been reported in rodent studies at effective doses
