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Description
Consider periodic monitoring of B12 in patients on metformin with risk factors for B12 deficiency Risk factors are quite wide-ranging and include the following (MHRA, 2022): Baseline vitamin B12 levels at the lower end of the normal range

The difference between a 98% pure peptide and an 85% pure one might seem minor, but that 13% impurity can include problematic compounds

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GLP-1/GIP receptor agonism versus NNMT enzyme inhibition

et al.: Methylmalonic acid in aging and disease (2024) Trends in endocrinology and metabolism: TEM | DOI: 10.1016/j.tem.2023.11.001.

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