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NICE guidelines recommend a structured approach beginning with lifestyle modification and progressing to pharmacological interventions when appropriate
Vitamin A
It tells us this isn't an ingredient class under active safety suspicion

Proc Soc Exp Biol Med 1958;97:780-4
[PMC free article] [PubMed] [Google Scholar] 4.Graham ID, Jette N, Tetroe J, Robinson N, Milne S, Mitchell SL
In addition, vitamin B12 methylcobalamin injections raise the available amount of SAMe (S-adenosylmethionine), an important compound which lifts the mood and works as a tricyclic antidepressant