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Most patients tolerate hydroxocobalamin injections well

(2024) 221(4):e20232104

Complement type 1 deficiency is pivotal in lupus development [14]

Excess B12 from oral supplements is poorly absorbed at high doses (the body absorbs roughly 1 to 2% of a 1,000 mcg oral dose) and the remainder is excreted in urine

Cell culture and drug treatment SH-SY5Y cells were obtained from ATCC (Manassas, VA, USA) and cultured in DMEM supplemented with 10% fetal bovine serum (FBS) and 1% penicillin-streptomycin, at 37 C in a humidified atmosphere with 5% CO 2

Vitamin B12 is primarily found in animal-based foods such as meat, dairy, and eggs