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Importantly, when combined with curcumin, 3,4-DHPV exhibited a strong synergistic anti-inflammatory effect at low micromolar concentrations (5 M 3,4-DHPV + 5 M curcumin), markedly reducing the expression of multiple pro-inflammatory genes (e.g., IL-6, MCP-1, COX-2, IL-1, TNF-, iNOS) and their secreted protein levels (Marcolin et al., 2025)

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Adenosylcobalamin is also important for maintaining healthy nerve function
Chem Biol Interact 1991

Access this chapter Subscribe and save Buy Now Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others Abbreviations DENA: Diethylnitrosamine DGD: Diglucosyldiacylglycerol IFN-: Interferon-gamma MCA: Methylcholanthrene ROS: Reactive oxygen species SOD: Superoxide dismutase THQ: Thymohydroquinone TNF-: Tumor necrosis factor- TQ: Thymoquinone References Abdallah EM (2017) Black seed (Nigella sativa) as antimicrobial drug: a mini-review