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Onset of solar elastosis of the scalp precedes the onset of hair loss in androgenetic alopecia,[38] providing the evidence that scalp hair does not completely protect from the effects of UVR and the need for added scalp UVR protection

Kulkarni A., Preeti K., Tryphena K

Antioxidants & Redox Signaling 11: 715724

This part matters because even something as simple as a vitamin shot isn't always symptom-free

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In the brain, the accumulation of homocysteine is correlated with increased total homocysteine and S-adenosylmethionine levels in cerebrospinal fluid