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Monitor for any return of symptoms and adjust accordingly
Electrophilic compounds, including toxins, reactive oxygen species, and phase I drug metabolites, commonly undergo glutathione conjugation for detoxification.
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Moreover, it has been shown that various cytotoxic chemotherapeutic drugs can promote autophagy in cancer cells, often impacting the cell's survival or death [102]
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In the GIMEMA study, 96 % of patients achieved CR with PML::RARA negativity at the end of consolidation
