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Sponsors play an important role in the efficiency of clinical trials

In cultured human cells exposed to heavy metals (Zn, Co, Ni) known to induce DNA breaks and strand instability, Epitalon significantly reduced the extent of genotoxic damage, acting as a protective agent [36]

10.1038/s41401-023-01153-z [DOI] [PMC free article] [PubMed] [Google Scholar] Sim H., Jung E., Lee D

Importantly, these early trials confirmed that AOD9604 did not affect blood glucose, insulin sensitivity, or IGF-1 production in humans, validating the laboratory findings

doi: 10.1038/srep36281

When Nrf2 is activated, it triggers the expression of enzymes involved in antioxidation and detoxification, protecting cells against oxidative stress
