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[PubMed: 16807770] 46

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These include hemodynamic overload, ventricular dysfunction secondary to ischemia and structural changes in the ventricular architecture

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However, like any supplement, potential side effects exist, though they're generally mild and infrequent: Gastrointestinal Upset: Some users may experience mild gastrointestinal discomfort, such as nausea, diarrhea, or stomach upset