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Detailed neuropsychological evaluation scores are for the PD and HC groups

Each feature was assigned a score from 0 to 3 based on its absence (0) or presence to a mild (1), moderate (2), or severe (3) degree, and a final histology score was determined [54]

These reactions are actually quite slow unless catalyzed by an enzyme such as protein disulfide isomerase (PDI), an important enzyme that is particularly abundant in the endoplasm reticulum where protein folding occurs
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For example, age- and disease-related downregulation of the miRNA biogenesis pathway in adult neurons reportedly can lead to changes in their survival, functions, and connectivity (68)

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