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APE/Ref-1 is a multifunctional protein in the DNA base repair pathway that is responsible for repairing apurinic/apyrimidinic sites in DNA after oxidation (Fritz et al., 2003)

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50 However, Chong et al showed that by triggering the Wnt1/-catenin pathway, erythropoietin (EPO) might shield endothelial cells (ECs) from high glucose exposure, indicating a protective function of Wnt1 in DKD

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