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Additionally, elevated expression levels of insulin-like development factor-1 and collagen type I were observed

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Various administration routes result in varying medication concentrations

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The most effective cerebral protection protocol integrates three components: (1) preoperative cerebrovascular reserve assessment, (2) intraoperative NIRS monitoring with protocolized interventions, and (3) maintenance of cerebral perfusion pressure through goal-directed fluid and vasopressor management (74)

While the cancer cells provide their microenvironment with secreted metabolites, sertraline treatment could target the galectin-1 mediated immunosuppressive marks of ser/gly metabolically dependent lung cancer [35, 67]