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As tirzepatide promotes substantial weight reductionclinical trials such as SURMOUNT-1 demonstrated average weight loss of approximately 20.9% of body weight at the 15 mg dose in adults without diabetesthis metabolic shift can influence the hypothalamic-pituitary-ovarian axis that regulates menstruation
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[DOI] [PMC free article] [PubMed] [Google Scholar] 30.Brcic L, Brcic I, Staresinic M, et al
Additional cellular stress-mediated benefits to vascular health have been demonstrated such as reductions in vascular fibrosis [9], attenuation of thrombus formation [10] and reductions in vascular inflammation and calcification [11, 12]

doi: 10.1007/s00604-018-2755-0
