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The selected microneedles formulation (LUT-EX@MN) exhibited the highest AUC value among all formulations with 5.3-fold increase in AUC compared to LUT-EX@gel

Jain et al., 2010

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doi: 10.3389/fendo.2025.1573526 Received 09 February 2025 Accepted 15 September 2025 Published 01 October 2025 Volume 16 - 2025 Edited by Claus Yding Andersen, University of Copenhagen, Denmark Reviewed by Gennaro Lettieri, University of Naples Federico II, Italy Anitha Myla, Mississippi State Department of Health, United States Updates Copyright 2025 Han and Jin

For this reason, the thyroid gland has developed an antioxidative defense system that is composed of antioxidative enzymes and free radical scavengers [130], comprising among others superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), and catalase (CAT), vitamins C and E, - and -tocopherols or coenzyme Q [124, 130]

Naturally produced in the liver, this powerful tripeptide (composed of three amino acids: glutamine, cysteine, and glycine) plays a crucial role in detoxification, cellular repair, and immune function