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The diagnosis of T2DM was based on the criteria of the World Health Organization (WHO 1999) [24]

There are also pleiotropic effects of some compounds which indirectly re-activate survival pathways (e.g., compensatory activation of other RTKs or augmented antioxidant defenses) which can suppress the net anticancer effect, and in extreme circumstances can temporarily maintain the survival of stressed malignant cells

Gastroenterology 153:448-459.e8

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Arch Phytopathology Plant Protect 44:712725 Dodds PN, Rathjen JP (2010) Plant immunity: towards an integrated view of plant-pathogen interactions

By modifying gene expression without changing the underlying DNA sequence, this process predominantly occurs in CpG islands, regions where cytosine is positioned next to guanine [147]