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Issues like pernicious anemia and some gut problems can also cause it

Supplements: Veterinarians may prescribe oral or injectable B12 supplements for dogs with malabsorption disorders such as exocrine pancreatic insufficiency (EPI) or chronic gastrointestinal disease

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These include a variety of subgroups such as Treg cells (or Tregs), Helper T (Th) cells, and CD8 CTLs [83]