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Some insurers require documented trial of oral supplementation before approving injections, though this contradicts the pathophysiology-patients with true intrinsic factor deficiency cannot absorb oral B12 regardless of dose

Use between 1 to 2.5 ml of solution for reconstitution unless specific studies confirm that a higher volume is safe

FAQs Q: Are they FDA-approved for weight loss

The pivotal primate study was published in Science Translational Medicine in 2011
