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How GLP-1 Medications Work and Why Weight Regain Happens GLP-1 receptor agonists like Zepbound slow gastric emptying, reduce hunger signaling in the brain, and increase feelings of fullness

These observations extend earlier work in which 5-HT 4 receptor mechanisms were shown to be involved in cholera toxin-induced mucin secretion (476)

It may be formed as part of the hyperplastic response

The medication works best when paired with a healthy diet, increased physical activity, and ongoing supervision