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Since venetoclax and AZD-5991 rapidly induce apoptosis in CLL cells, these compounds were added in the last 24 hours of incubation to minimize single-drug cytotoxicity

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Background A leading biopharmaceutical company was developing a novel antibody-drug conjugate aimed at achieving precise drug release for specific tumor types

The results were examined in accordance with different models: zero, first-order kinetic models, and Higuchi diffusion

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