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While our research elucidates the pivotal role of MFAP2 secreted by CAFs in promoting CRC progression and immune evasion, it is critical to acknowledge that immune cell activity can also be autonomously regulated or directly modulated by CRC cells during tumor progression [10]
Ghavami S, Shojaei S, Yeganeh B, et al
Mol Pharmacol 60, 847856 (2001)
doi: 10.3390/ijms18030506 98
These facts seem to establish a link between folic acid and pulmonary fibrosis
(3) IGF1R upregulates LDHA via the JAK2/STAT3 pathway, influencing glycolytic metabolism and subsequently promoting EMT progression
