increasing glutathione synthesis Glutathione-Dependent Pathways in Cancer Cells Two-step enzymatic reaction of glutathione

Bieluszewski T, Prakash S, Roul T, Wagner D

doi: 10.1002/pbc.26783 150 UppuluriRSivasankaranMPatelSSwaminathanVVRamananKMRavichandranNet al

Overall, structural alterations found in SURF1 and other LS mutant organoids confirmed the dysregulation of NPCs function and morphogenesis as a relevant mechanism in the pathophysiology of LS

ROS are signaling molecules that induce the release of pro-inflammatory cytokines [6], and the dysregulation of this response plays an essential role in the development of inflammation [7]

Zhu, T., Zheng, S

ATP-binding cassette (ABC) transporters mediate chemotherapy resistance but their role in modulating the activity of targeted small-molecule inhibitors is unclear