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Zhongguo Yi Xue Ke Xue Yuan Xue Bao 24:185187 Noland RC, Koves TR, Seiler SE, Lum H, Lust RM, Ilkayeva O, Stevens RD, Hegardt FG, Muoio DM (2009) Carnitine insufficiency caused by aging and overnutrition compromises mitochondrial performance and metabolic control

Once nAbs did emerge in this group, the responses targeted epitopes known to be involved in CD81 binding, and rapidly drove a decrease in binding efficiency, likely as a result of the emergence of immune escape mutations

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Effects on stability, immunoreactivity, and catalytic properties