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USA 109 , 55235528 (2012)

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Growing Life cycle Annual Light requirements Full sun Soil Peaty, Well-drained Soil pH 6.1 6.5 (Slightly acidic), 6.6 7.3 (Neutral) Growing habitat Cool temperate regions USDA Plant Hardiness Zones 2a, 2b, 3a, 3b, 4a, 4b, 5a, 5b, 6a, 6b, 7a, 7b, 8a, 8b, 9a, 9b, 10a, 10b, 11a, 11b Planting time Early spring, Fall Plant spacing average 0.3 m (0.98 ft) Growing time 95-100 days Potential insect pests Aphids, Moths, Slugs, Cabbage loopers, Flea beetles, Snails Potential diseases Leaf spot, Black rot, Club root Brussels sprouts are biennials but are usually treated as annuals

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HIF hydroxylation and the mammalian oxygen-sensing pathway
It is classified as a conditionally essential amino acid, predominantly synthesized in skeletal muscle, where it constitutes the largest proportion of free amino acids