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[DOI] [PubMed] [Google Scholar] 84.Marcuard S.P., Sinar D.R., Swanson M.S., Silverman J.F., Levine J.S

Treatment doses depend on the cause: pernicious anaemia typically requires intramuscular hydroxocobalamin 1,000 micrograms three times weekly initially, whilst dietary deficiency may be treated with oral cyanocobalamin 50150 micrograms or 1,000 micrograms daily

Additionally, trials of oligonucleotide therapeutics and some small-molecule NNMT inhibitors in vitro and in preclinical animal models have validated NNMT as a promising therapeutic target to prevent or treat obesity and related T2D, but currently, clinical trials have not yet been reported

StatPearls .

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Upon encountering these symptoms, consult your doctor right away