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They determine growth and pubertal development in childhood and predispose the individual for developing the metabolic diseases and malignancies in adult life, as predicted by the Barker hypothesis

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In the gastrointestinal (GI) tract following oral ingestion, systemic uptake of Cr(VI) competes with the rapid extracellular reduction to Cr(III) by gastric juices (Proctor et al., 2012