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This established Leydig cell model allowed for controlled induction of senescence and testing of FOXO4-DRI effects

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Mouse prostatic epithelial cells are stimulated by pattern recognition receptor (RRR) ligands to produce inflammatory cytokines like TNF-, IL-6, and CXCL10, and bacterial components activate TLR4 and TLR5 signaling pathways to cause these chemokines in PECs (Fig

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If the topics above reflect ongoing symptoms or unanswered concerns, a brief conversation can help clarify whether a root-cause approach is appropriate