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Activation of promoter activity of the catalytic subunit of -glutamylcysteine ligase (GCL) in brain endothelial cells by insulin requires antioxidant response element 4 and altered glycemic status: implication for GCL expression and GSH synthesis

Esta combinacin crea un efecto sinrgico donde cada principio activo amplifica la eficacia de los dems, acelerando los resultados visibles comparado con tratamientos monoteraputicos

Loss of Lgr5 + stem cells in response to severe (often transmural) injury requires additional regenerative capacities in the intestine, involving quiescent slow-cycling cells located at the +4 position in the crypt, de-differentiated epithelial cells and reserve stem cells 35

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Active caspase 3 and protein levels of GSDME-N were increased in tongue squamous cell carcinoma, whereas full-length GSDMD was reduced under light irradiation, demonstrating the potential of Th-M to initiate pyroptosis

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