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2020JJ4138), Hunan Furong Scholars Program, Hunan Youth Excellent Talents Supporting Program (No

In addition, as mentioned in Section Errors in the protein synthesis pathway, the age- and AD-associated increases in +1-frameshifted ubiquitin B can block polyubiquitination and lead to an impairment in UPS function

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CAQK-treated mice also showed significantly reduced apoptosis, as measured by TUNEL staining in the injured areas (Fig

Clinical implication The updated FDA labeling for liraglutide and semaglutide highlights the importance of monitoring depressive symptoms or suicidal thoughts, suggesting treatment discontinuation if such ideations occur [87,88]