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10.1006/excr.1995.1056 Exp

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Collectively, these effects work to reduce widespread hyperalgesia and support adaptive neuroplasticity, effectively recalibrating the hypersensitive CNS [402]

Gout, a form of inflammatory arthritis known for causing excruciating pain in the big toe, stems from a buildup of uric acid (urate) in the body that crystallizes and settles in one or more joints

Beyond its antioxidant work, it helps the body process environmental toxins and supports a healthy immune response

While ETC is the source of superoxide, the existence of mitochondrial NO synthase (mtNOS) that provides the NO required to form peroxynitrite is controversial