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Using the arginine deiminase analog ADI-PEG-20 in hepatocellular carcinoma and glioblastoma has demonstrated antitumor activity in vitro and in xenograft models and demonstrated safety and efficacy in a phase I clinical trial

Reduced HDL-PON1 levels are also found in other cardiometabolic diseases, including type 2 diabetic mellitus (T2DM) (866,867), type 1 diabetes mellitus (T1DM) (868), rheumatoid arthritis (RA) (869,870), dyslipidemia (e.g

[DOI] [PMC free article] [PubMed] [Google Scholar] Hays GL, Bullock Q, Lazzari EP, Puente ES

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[DOI] [PMC free article] [PubMed] [Google Scholar] 77.Amiri R., Tabandeh M.R., Hosseini S.A