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Thus, SPIONs can be used up to a concentration of 65.06 mg/L in the culture water of Labeo rohita and its toxicity at higher doses can be partially ameliorated by feeding of vitamin E (at 250 mg/kg feed) for 15 days during post exposure period

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Three studies implicated matrix metalloproteinases, with one study demonstrating vascular endothelial growth factor overexpression