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Among existing signaling pathways, the mitogen-activated protein kinase (MAPK) and nuclear factor-B (NF-B) signaling pathways are key regulators of inflammatory processes

Furthermore, the upregulation of miR-7116-5p in mouse microglia impedes the synthesis of TNF- and activation of glial cells, thereby offering additional defense against the degeneration of DA neurons

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C.LiL.StenderH.NezirogluN.RichterC.et al (2015)

However, HIF-1 is considered as a potential regulator of intestinal permeability during regular exercise-induced hypoxia (Yu et al., 2022)

Bottom panel: The activity of natural killer cells (NK cell cytotoxicity) increased at weeks 2 and 4 for both the low-dose (gray bars) and high-dose (striped bars) groups