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Although keeping sulfide concentrations in the narrow therapeutic range appears to be critical, currently available pharmacological tools (e.g., inhibitors of H 2 S-producing enzymes) fail to achieve this goal

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[0211] Embodiment 204: The chimeric antigen receptor of embodiment 202, wherein said costimulatory signaling region comprises 4-1BB

Each drug has different mechanism of action and a different way to decrease the breakdown of acetylcholine which is an important neurotransmitter in the brain [123]

10.1021/bi00418a059

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