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Tendon and ligament recovery: Patients with rotator cuff injuries, Achilles tendinopathy, patella tendon issues, plantar fasciitis, and other chronic tendon injuries that have not responded adequately to rest and physical therapy

The mechanism involves upregulation of VEGF expression a key growth factor in new blood vessel formation and activation of ERK1/2 signaling pathways that drive cell proliferation, migration, and angiogenesis

Marcassa, E., Kallinos, A., Jardine, J., Rusilowicz-Jones, E

Preparation and functional evaluation of RGD-modified proteins as v3 integrin directed therapeutics

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Chen H-W, Huang C-S, Li C-C et al (2014) Bioavailability of andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats