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This strategy could significantly improve the therapeutic potential of these natural compounds for patients suffering from IC

However, 5-FU exerts general toxicity on normal proliferating cells due to 5-FdUTP and dUTP misincorporation into DNA and 5-FUTP into RNA 24

[DOI] [PubMed] [Google Scholar] 168.Bota B

Parikh AR, Gonzalez-Gugel E, Smolyakova N, Jen MH, Toms N, Lin Y, Kim JS, Kopetz S

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