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doi: 10.1007/s00425-024-04577-x 123 RajputP.UrfanM.SharmaS.HaklaH

L-theanine intake (6 mg/kg) could prevent brain atrophy and stress vulnerability in senescence-accelerated mice prone 10 (SAMP10) mice, with the mechanism of intaking L-theanine could block the expression changes of the transcription factor neuronal PAS domain protein 4 ( Npas4 ) and Lipocalin 2 ( Lcn2 ) in hippocampus and PFC of SAMP10 (58)

In yeast, Ubc1 (mammalian homologous UBE2K) facilitates the formation of K48/K63-branched ubiquitin chains and regulates resistance to heat shock and DNA replication stress (Pluska et al, 2021)

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