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This has shown the protective effect of taurine, indicating that it may be a potential approach for managing oxidative damage during aging as it averted the reduction of the antioxidant enzyme superoxide dismutase (122)

Cognitive performance among the elderly and dietary fish intake: the Hordaland Health Study

The efficacy of a second-generation derivative, omaveloxolone (RTA408), has recently been assessed in a preclinical model for diabetic chronic non-healing wounds [277] and, interestingly, omaveloxolone is now being tested in phase-II clinical trial for the Friedreichs ataxia (FRDA), a neurodegenerative condition in which NRF2 activation is suppressed [278, 279]
Update: Prof Francis shows in this tweetorial that a hard outcome trial will include 150,000 patients and cost $3 billion dollars

Notwithstanding, BSO-treated mice rapidly underwent weight loss (15% reduction at 24 h)

treatment difference 10.2%
