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The efficacy of compounds with such a broad spectrum of mechanisms of action confirms the complexity of ASD as a disorder [120]

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Though discrepancy exists under these conditions, a common requirement of Ca 2+ necessitates PAD4 activation through the pore-forming proteins, such as MLKL, GSDMD and GSDME 53,54,55,56

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[DOI] [PubMed] [Google Scholar] 102.Ricciolini R, Scalibastri M, Kelleher JK, Carminati P, Calvani M, Arduini A

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