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Research has also shown that under serine-deficient conditions, pancreatic ductal adenocarcinoma (PDAC) cells maintain intracellular serine levels by upregulating PHGDH, adapting to the harsh microenvironment and promoting tumor progression (74)
Okuda, Y., Okuda, M
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albicans can induce a masking phenomenon on its surface -glucan through the mitochondrial and cAMP-protein kinase A signaling pathways, thereby avoiding recognition and attack by host immune cells (such as macrophages), significantly enhancing its immune evasion ability and pathogenic survival potential in the host (Pradhan et al., 2018)

Antiinflammatory effects arise through inhibition of NFB and MAPK signaling, reducing levels of COX2, IL6, and TNF in the tumor microenvironment

G., Major, A
