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Lower Acitivity of Superoxide Dismutase and High Activity of Glutathion Reductase in Erythrocytes From Centenarians Age and Ageing, 1998

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This suggests that components beyond HCl, such as pepsin, bile acids and trypsin, alongside, may play significant roles in GERD pathophysiology (Reference Li, Xu and Zhou10) , in addition to factors such as low adherence to treatment and the presence of functional heartburn (Reference Mermelstein, Chait Mermelstein and Chait11)

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