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Clonal Evolution in Relapsed Acute Myeloid Leukaemia Revealed by Whole-Genome Sequencing

However, the dose of polyphenols alone is not a crucial factor when considering the toxic potential of phenolic compounds, as it also depends on the time of exposure and possible synergistic effects

Pawelczyk T, Grancow-Grabka M, Trafalska E, Szemraj J, Zurner N, Pawelczyk A (2018) Telomerase level increase is related to n-3 polyunsaturated fatty acid efficacy in first episode schizophrenia: secondary outcome analysis of the OFFER randomized clinical trial

2018s textbook Animal Physiology describes this concept in more depth

49 Additionally, we evaluated the association rate constants, k on , which are dominated by the diffusive properties of the partners and geometric constraints of the actual binding, for the three complexes by applying the expression, where N A is Avogadros number, V eff is the effective volume of a half-sphere with radius r eff around the tip, which describes the effective volume for proteins binding, and t 0.5 is the time required for the half-maximal binding probability