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the treatment with doxorubicin in GSH-modified PEGylated liposomes showed a strong significant reduction in brain tumour growth compared to saline and non-modified PEGylated liposomes in time (2-way ANOVA, p 0.001), and in a highly significant survival benefit when compared to the control groups (increase of 42% as compared to saline and 19% compared to non-modified PEGylated liposomes)

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doi: 10.1016/j.metabol.2014.02.009 44

Here, our genetic screening of the previously constructed hairpin RNA-based Arabidopsis library identifies a glutathione (GSH)-deficient mutant that has high accumulation of glutamate (Glu), a previously defined wound signal essential for activating plant defense, but disharmoniously exhibits attenuation of defense signaling events

Variants of this gene can affect the activity of the SOD2 enzyme, and therefore alter the rate at which we clear away reactive oxygen species (ROS)