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In a PCOS theca cell model, PA disrupts mitochondrial function and induces ROS production, activating the ROS/p38 and JNK signaling pathways, which promote androgen production and ovarian fibrosis [58]

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GSH reacts with ROS species and gets transformed to GSSG causing a decline in GSH/GSSG ratio that results in oxidative stress 10,11

By combining antioxidant protection, melanin-pathway support, and pigment-signal disruption, L Glutathione Tranexamic Acid Ascorbic Acid offers a multi-angle approach to managing dullness, dark spots, and uneven skin tone without requiring a prescription

20: Lands LC, Grey V, Smountas AA, Kramer VG, McKenna D (1999)

Belosludtsev KN, Belosludtseva NV, Dubinin MV
